Blood sugar supplements
Stable blood sugar levels are crucial for your health. They help maintain your energy levels and support a healthy metabolism.
As you know, healthy nutrition and plenty of exercise are the basis for achieving this.
But did you know that there are also natural supplements that can contribute to healthy blood sugar levels?
Blood sugar supplements contain plant extracts that help stabilize your blood sugar in a gentle and natural way.
Why is it important to keep your blood sugar levels stable?
An imbalance in blood sugar levels can be harmful in both the short and long term.
- Short-term effects include fatigue, hunger, thirst, frequent urination, and difficulty concentrating.
- Long-term disruptions can lead to serious health problems such as type 2 diabetes, cardiovascular disease, kidney damage, nerve damage and eye problems.
It is important to keep your blood sugar levels balanced to prevent these risks.
Blood sugar supplements
These 3 plant extracts have been proven effective in supporting healthy and stable blood sugar levels:
1. Nopal Cactus Extract (Neopuntia®)
Neopuntia® extract, derived from the Mexican nopal cactus (Opuntia ficus-indica), supports your cholesterol and helps keep your blood sugar levels stable.*
This cactus is rich in fiber, which slows down the absorption of sugar, preventing your blood sugar levels from rising too quickly. This contributes to a balanced metabolism. * (1) (2)
Nopal Premium (with Nopal and Chrome)
In our Nopal Premium supplement, we combine this powerful cactus extract with chromium picolinate. Together, these ingredients form an effective duo that contributes to stable blood sugar levels.
The supplement is sustainably produced, with an eye for fair prices for farmers.
2. Chromium picolinate
Chromium is a mineral you get through your diet. It's essential for regulating your blood sugar levels. However, your body only absorbs a small percentage of the chromium in your food.
This is why people with reduced chromium levels, such as those with type 2 diabetes, may benefit from supplementing with chromium picolinate, a highly absorbable form of chromium.
Scientific research shows that a dosage of 200 mcg per day or more is effective. (3) (4)
3. Rebersa® Berberine Extract
Berberine is a powerful, natural substance from the barberry plant (Berberis) that helps improve insulin sensitivity. *
It not only supports your blood sugar levels, but also your cholesterol and fat metabolism. *
For people who do not tolerate statins (cholesterol-lowering drugs), berberine can be a good alternative. It helps lower cholesterol without many side effects. (5) (6)
Berberine usually takes effect after three months and is a natural option for people who want to regulate their cholesterol without medication.
Rebersa® is a high-quality berberine extract from Rabinsa, with a purity of at least 97%. It has proven effectiveness and a high concentration. The recommended dosage is 3 x 500 mg per day.
Good to know: Claims marked with (*) are health claims that are still awaiting European approval.
Sources used
- López-Romero, P., Pichardo-Ontiveros, E., Avila-Nava, A., Vázquez-Manjarrez, N., Tovar, A.R., Pedraza-Chaverri, J., & Torres, N. (2014). The Effect of Nopal (Opuntia Ficus Indica) on Postprandial Blood Glucose, Incretins, and Antioxidant Activity in Mexican Patients with Type 2 Diabetes after Consumption of Two Different Composition Breakfasts. Journal Of The Academy Of Nutrition And Dietetics , 114 (11), 1811–1818. https://doi.org/10.1016/j.jand.2014.06.352
- Kashif, R. R., D'Cunha, N. M., Mellor, D. D., Alexopoulos, N. I., Sergi, D., & Naumovski, N. (2022). Prickly Pear Cacti (Opuntia spp.) Cladodes as a Functional Ingredient for Hyperglycemia Management: A Brief Narrative Review. Medicina , 58 (2), 300. https://doi.org/10.3390/medicina58020300
- Suksomboon, N., Poolsup, N., & Yuwanakorn, A. (2014). Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes. Journal Of Clinical Pharmacy And Therapeutics , 39 (3), 292–306. https://doi.org/10.1111/jcpt.12147
- A scientific review: the role of chromium in insulin resistance. (2004). PubMed. https://pubmed.ncbi.nlm.nih.gov/15208835/
- Ye, Y., Liu, X., Wu, N., Han, Y., Wang, J., Yu, Y., & Chen, Q. (2021). Efficacy and Safety of Berberine Alone for Several Metabolic Disorders: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Frontiers in Pharmacology , 12 . https://doi.org/10.3389/fphar.2021.653887
- Nazari, A., Ghotbabadi, Z. R., Kazemi, K. S., Metghalchi, Y., Tavakoli, R., Rahimabadi, R. Z., & Ghaheri, M. (2023). The Effect of Berberine Supplementation on Glycemic Control and Inflammatory Biomarkers in Metabolic Disorders: An Umbrella Meta-analysis of Randomized Controlled Trials. Clinical Therapeutics , 46 (2), e64–e72. https://doi.org/10.1016/j.clinthera.2023.10.019
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bloggleThe best berberine? Here's what to look for.
How do you choose a berberine supplement that truly works? Not all supplements are equally pure or easily absorbed, and making the right choice can be difficult. In this blog, I'll show you what to look out for so you can be sure you choose a high-quality and effective supplement. Choose berberine from natural sources with Rebersa® (≥500 mg) for optimal absorption and effectiveness. Berberine supports cholesterol and blood sugar, but definitive conclusions about weight management require further research. Berberine Premium from Natuurlijk Presteren is a favorite thanks to high-quality Rebersa®, the correct dosage, favorable price and minimal side effects. Table of contents Criteria for a good berberine supplement The top 3 best berberine supplements #1 – Berberine Premium - Natural Performance #2 – Berberine 500 - Vitakruid #3 – Berberine 500 - Vitals What are the benefits of berberine? Does berberine help with weight loss? When is the best time to take berberine? What is the effect of berberine on the intestines? Potential side effects of berberine Conclusion: The best choice for berberine supplements Criteria for a good berberine supplement Here are the three most important things I look for to ensure I choose a top-quality berberine supplement: Extracted from a natural source - A quality supplement contains berberine from natural sources, such as the Berberis plant. Synthetic versions may be less pure or contain undesirable substances. That's why I always check the source on the label. Contains the best form: Rebersa® Berberine - Not all berberine is created equal. Rebersa® Berberine is known for its purity and high bioavailability, meaning your body absorbs it better. This ensures a more powerful effect without unnecessary additives. Has the right dosage: 500 mg per capsule - For an effective dosage, I look at 500 mg per capsule. This is a common amount used in scientific studies because it is both effective and safe. In short : A good berberine supplement is pure, easily absorbed, and has an effective dosage. By checking the source and ingredients, you can be sure you're choosing a truly good product! The top 3 best berberine supplements Based on these criteria, I found the 3 best berberine products available right now: #1 – Berberine Premium - Natural Performance Berberine Premium from Natuurlijk Presteren contains the best form of berberine, from a natural source and in the ideal dosage. Thanks to the 100% plant-based capsule, it's also suitable for vegans. This premium supplement is without a doubt number 1, because of the top quality berberine, correct dosage and purity. #2 – Berberine 500 - Vitakruid This berberine supplement from Vitakruid also meets all the important criteria: it contains natural berberine, the Rebersa® form and the ideal dosage of 500 mg. The benefits: With only natural berberine Contains the best form of berberine: Rebersa® Ideal dosage of 500 mg Disadvantage The price is a lot higher. This product is available at bol.com, among others. The only drawback is the higher price, but the quality is good, giving this product a deserved second place. #3 – Berberine 500 - Vitals Like numbers 1 and 2 in this comparison, the Vitals brand offers a high-quality berberine supplement that meets all the criteria. The benefits: With only natural berberine Contains the best form of berberine: Rebersa® Ideal dosage of 500 mg Disadvantage The price is a lot higher. This product is available at bol.com, among others. Berberine 500 from Vitals is a reliable choice. But if you want the best deal, then Berberine Premium from Natuurlijk Presteren is the smartest option. What are the benefits of berberine? Researchers have been studying the properties of berberine and the role it can play in a healthy lifestyle for years. This is what is known so far: It contributes to healthy cholesterol levels (*). It helps maintain stable blood sugar levels (*). Berberine is being studied for its possible effects on liver function and urinary tract health (*). It may play a role in healthy stomach function (*). Berberine supports the natural regeneration of the skin (*). Good to know : (*) Health claim pending approval by the European Commission. Does berberine help you lose weight? Much research is being done on the potential role of berberine in weight management, but there is not enough scientific evidence to draw definitive conclusions. So far, there are only suspicions that berberine can influence various processes that are important for weight management, such as blood sugar regulation, fat storage and intestinal flora. (1) (2). Research is therefore primarily conducted into these connections. Remember : A healthy lifestyle with a balanced diet and regular exercise remains the most important factor for maintaining a healthy weight. When is the best time to take berberine? It is best to take berberine on an empty stomach just before a meal . This has several advantages: Improved recording Fewer side effects (such as stomach complaints) A typical daily dose is between 1000 and 1500 mg. It's best to divide this dose between meals, for example, two to three 500 mg capsules. What is the effect of berberine on the intestines? Scientists are also investigating how berberine affects our intestines and metabolism. While we don't know everything yet, there have already been some interesting discoveries. It appears that berberine is good for the intestinal flora. And that could well be the key to many of berberine's benefits, as our gut bacteria play an important role in several aspects of our health, from our immune system to our metabolism. (3) Berberine may possibly influence: The composition and functioning of your intestinal bacteria How Your Body Absorbs Berberine The health of the intestinal wall (4) More research is needed to determine this with certainty, and I look forward to telling you more about this in the future! Potential side effects of berberine Berberine is generally well tolerated (especially when you stick to the recommended amounts), but it can potentially cause some side effects. The most common ones are: Stomach and intestinal complaints - Such as diarrhea, constipation, flatulence and nausea. Lower blood pressure – This can be beneficial for some people, but problematic for others. These side effects are usually mild and often disappear over time. It is important to exercise caution during pregnancy or breastfeeding, as there is insufficient research into safety in these cases. Note : Berberine may interact with certain medications, such as blood thinners and medications commonly used for diabetes. It may also affect the breakdown of medications in the liver, which could alter their effectiveness. Conclusion: The best choice for berberine supplements When choosing a berberine supplement, it is important to pay attention to the source, form (such as Rebersa®), and dosage. The Berberine Premium from Natuurlijk Presteren is the best choice because of its high quality, good absorption, natural ingredients and the best price. If you are willing to pay a little more, the supplements from Vitakruid and Vitals are also excellent options. In short, for a high-quality and effective supplement, it is best to choose Berberine Premium. Ebrina van der Bijl Ebrina is a nutritionist with a deep commitment to healthy eating and a sustainable lifestyle, based in beautiful Portugal. Her passion for natural and organic products is at the heart of her work. With a background in Nutrition & Dietetics and experience in product development and writing, she translates complex scientific information into practical advice for a balanced lifestyle. Read more Sources used Ilyas, Z., Perna, S., Al-Thawadi, S., Alalwan, T.A., Riva, A., Petrangolini, G., Gasparri, C., Infantino, V., Peroni, G., & Rondanelli, M. (2020b). The effect of Berberine on weight loss in order to prevent obesity: A systematic review. Biomedicine & Pharmacotherapy, 127, 110137. https://doi.org/10.1016/j.biopha.2020.110137 Asbaghi, O., Ghanbari, N., Shekari, M., Reiner, Ž., Amirani, E., Hallajzadeh, J., Mirsafaei, L., & Asemi, Z. (2020). The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials. Clinical Nutrition ESPEN, 38, 43–49. https://doi.org/10.1016/j.clnesp.2020.04.010 Zhang, Y., Gu, Y., Ren, H., Wang, S., Zhong, H., Zhao, X., Ma, J., Gu, . . Wang, W. (2020b). Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study). Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-18414-8 Zhang, L., Wu, X., Yang, R., Chen, F., Liao, Y., Zhu, Z., Wu, Z., Sun, X., & Wang, L. (2021). Effects of Berberine on the Gastrointestinal Microbiota. Frontiers in Cellular And Infection Microbiology, 10. https://doi.org/10.3389/fcimb.2020.588517
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bloggleBerberine: What is it and what are its benefits?
Have you ever heard of berberine ? This natural plant extract has been an important part of traditional Chinese medicine for centuries. Nowadays, it is increasingly seen in supplements and is gaining more attention because of its potential health benefits. But what exactly is berberine, and why is it mentioned so often in the world of supplements? In this article, you'll discover everything about berberine, what it is, and what it can do for your health. Berberine is a plant alkaloid that is good for cholesterol, blood sugar levels and liver function. There are several forms of berberine (HCL, sulfate, liposomal), but Berberine HCL is the most researched and the most effective. Capsules containing Rebersa® Berberine HCL (97% purity) are the most effective and consistent. This is also the best, patented form of berberine available worldwide. Table of contents What is berberine? The benefits of berberine 1. Berberine supports normal cholesterol levels* 2. It contributes to the maintenance of healthy blood sugar levels* 3. Berberine is good for the urinary tract and liver* 4. Berberine is good for normal stomach function* 5. Berberine supports the skin’s regenerative capacity* Natural sources of berberine What types of berberine are there (in supplements)? What is the best berberine? Berberine powder or capsules? What is berberine? Berberine is a natural substance found in various plants in the Berberidaceae family. One of the best known is the barberry shrub , also known as barberry in the Netherlands. It has a yellow color and a bitter taste. The roots, bark, and rhizomes of the plant have been used in traditional medicine for centuries, especially in Asia. What makes berberine particularly special is its chemical composition. It belongs to the group of alkaloids , substances that contain nitrogen. These compounds appear to influence various bodily processes, making berberine a popular subject for research. The benefits of berberine Research into the health benefits of berberine is still ongoing, but there are already promising results. Below you can read the most well-known benefits of berberine so far: 1. Berberine supports normal cholesterol levels* Berberine can help maintain healthy cholesterol levels. This is due to its influence on enzymes in the liver involved in processing fats and cholesterol. Additionally, berberine may affect the way your body processes glucose, which can contribute to a healthier lipid profile, or the balance of fats in your blood, such as cholesterol and triglycerides (1). 2. It contributes to the maintenance of healthy blood sugar levels* Research suggests that berberine may have a positive effect on glucose metabolism in the body. This may be especially relevant for people who want to control their blood sugar levels. (2) (3) 3. Berberine is good for the urinary tract and liver* Studies show that berberine can help maintain normal liver function. It can help maintain healthy levels of certain liver enzymes, which is important for a well-functioning liver. (4) In addition, berberine may play a supportive role in maintaining normal urinary tract function. It can support the body's natural defense mechanisms, which can help maintain a healthy urinary system. (5) 4. Berberine is good for normal stomach function* Animal studies suggest that berberine may support normal stomach function, perhaps through its anti-inflammatory properties. However, this effect has not yet been fully proven in humans (6). Further studies are needed to determine whether these effects also apply to humans. 5. Berberine supports the skin's regenerative capacity* Berberine has antimicrobial, antioxidant, and anti-inflammatory properties that may benefit skin health. (2) However, more research is needed to confirm these potential benefits. Good to know : (*) Health claim pending approval by the European Commission. Natural sources of berberine Berberine occurs naturally in several plants, but it is not commonly used as a food because of its bitter taste. Instead, it is mainly used in traditional medicine in the form of infusions, powders, or topical applications to treat various health conditions. Some well-known natural sources of berberine include (8): Barberry – Berberis vulgaris Oregon Grape (Grape Bush) – Mahonia aquifolium Indian barberry (Tree turmeric) – Berberis aristata Chinese gold thread – Coptis chinensis Canadian turmeric – Hydrastis canadensis What types of berberine are there (in supplements)? To use berberine in supplements, it is usually extracted from these plants and sometimes further processed to make it more absorbable by your body. There are different forms of berberine supplements available: Berberine HCl, Berberine sulfate, and Liposomal berberine are the most common. But which one is actually the best choice? Let's take a look! Berberine HCL - The most common form in supplements. The HCl form of berberine means it's combined with hydrochloric acid (HCl), which can aid in solubility and absorption. Plus, most research has been conducted with this form. A solid choice! Berberine Sulfate - A bit of an outsider. It's very similar to HCL, but less is known about it. Therefore, you won't encounter it very often. Liposomal berberine - Liposomal berberine is encapsulated in small fat globules, making it easily absorbed by the body. However, it is more expensive and less widely available. What is the best berberine? If you're looking for high-quality berberine, Rebersa® Berberine is the best choice. This patented extract is used in some of the best berberine supplements, such as Berberine Premium from Natuurlijk Presteren. Rebersa® is known for its impressive purity of at least 97% and is sustainably sourced from the roots of the barberry (Berberis vulgaris). The extract was developed by Sabinsa, a company that has spent years researching the best methods for extracting and purifying berberine. It is an excellent choice for those looking for reliable and powerful support for, for example, blood sugar and cholesterol levels. Berberine powder or capsules? You can take berberine as a powder or capsules, but I recommend capsules . They make it easier to maintain a consistent dosage. This is because capsules contain a fixed amount of berberine, so you know exactly how much you're taking each time. This is especially useful for people who want to follow a strict routine and don't want to worry about measuring the dose. Moreover, not everyone likes the taste of the powders. A capsule is often more pleasant because you don't taste the flavor. Ebrina van der Bijl Ebrina is a nutritionist with a deep commitment to healthy eating and a sustainable lifestyle, based in beautiful Portugal. Her passion for natural and organic products is at the heart of her work. With a background in Nutrition & Dietetics and experience in product development and writing, she translates complex scientific information into practical advice for a balanced lifestyle. Read more Sources used Ju, J., Li, J., Lin, Q., & Xu, H. (2018). Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials. Phytomedicine, 50, 25–34. https://doi.org/10.1016/j.phymed.2018.09.212 Nazari, A., Ghotbabadi, Z. R., Kazemi, K. S., Metghalchi, Y., Tavakoli, R., Rahimabadi, R. Z., & Ghaheri, M. (2023). The Effect of Berberine Supplementation on Glycemic Control and Inflammatory Biomarkers in Metabolic Disorders: An Umbrella Meta-analysis of Randomized Controlled Trials. Clinical Therapeutics, 46(2), e64–e72. https://doi.org/10.1016/j.clinthera.2023.10.019 Xie, W., Su, F., Wang, G., Peng, Z., Xu, Y., Zhang, Y., Xu, N., Hou, K., Hu, Z., Chen, Y., & Chen, R. (2022). Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.1015045 Nie, Q., Li, M., Huang, C., Yuan, Y., Liang, Q., Ma, X., Qiu, T., & Li, J. (2024). The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review. Journal Of Translational Medicine, 22(1). https://doi.org/10.1186/s12967-024-05011-2 Petronio, G. P., Cutuli, M. A., Magnifico, I., Venditti, N., Pietrangelo, L., Vergalito, F., Pane, A., Scapagnini, G., & Di Marco, R. (2020). In Vitro and In Vivo Biological Activity of Berberine Chloride against Uropathogenic E. coli Strains Using Galleria mellonella as a Host Model. Molecules, 25(21), 5010. https://doi.org/10.3390/molecules25215010 Choo, B. K., & Roh, S. (2013). Berberine protects against esophageal mucosal damage in reflux esophagitis by suppressing proinflammatory cytokines. Experimental And Therapeutic Medicine, 6(3), 663–670. https://doi.org/10.3892/etm.2013.1202 Hu, Q., Peng, Z., Li, L., Zou, X., Xu, L., Gong, J., & Yi, P. (2020). The Efficacy of Berberine-Containing Quadruple Therapy on Helicobacter Pylori Eradication in China: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Frontiers in Pharmacology, 10. https://doi.org/10.3389/fphar.2019.01694 Funk, RS, Singh, RK, Winefield, RD, Kandel, SE, Ruisinger, JF, Moriarty, PM, & Backes, JM (2017). Variability in Potency Among Commercial Preparations of Berberine. Journal Of Dietary Supplements, 15(3), 343–351. https://doi.org/10.1080/19390211.2017.1347227
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Rebersa Berberine: The Benefits and What Makes It Unique?
Berberine is a popular natural supplement that's gaining traction. And rightly so. It's being studied for its potential to support healthy cholesterol and blood sugar levels.* In this article, I'll tell you why Sabinsa's patented Rebersa® Berberine extract is so highly valued compared to standard berberine supplements. Rebersa® Berberine is a patented extract with a minimum of 97% purity, ensuring consistent dosages and reliable performance in every supplement. Thanks to LongLifeLipoTech™ technology, berberine is released gradually, reduces stomach irritation and the liposomal packaging supports better absorption in the body. Rebersa® is safe at 500–1500 mg daily, has few side effects, and contains no unnecessary fillers or contaminants, ensuring the reliability of the supplement. Table of contents What is berberine? What is Rebersa® berberine? These are the unique benefits of Rebersa® berberine : 1. Gentler on your stomach 2. Better absorption 3. Safe and clean 4. High purity and consistent quality How does Rebersa® berberine work? Buy Rebersa® berberine: Discover Berberine Premium What is berberine? Berberine is a natural substance found in the roots, stems, bark, and berries of the barberry plant (Berberis). It has been used for centuries in traditional Chinese and Ayurvedic herbal preparations. Today, berberine is also rapidly gaining popularity in the West, thanks to growing scientific research and the attention of biohackers and anti-aging experts. Berberine is extracted using modern techniques to ensure high purity in supplements, such as the Rebersa® extract. What is Rebersa® berberine? Rebersa® Berberine is a patented extract from the Sabinsa company. Sabinsa developed Rebersa® as a high-quality extract with a purity of at least 97%. This means the extract contains very pure berberine, extracted from the roots of Berberis aristata (Indian barberry). This purity ensures consistent performance and reliable dosing with every supplement using Rebersa®. These are the unique benefits of Rebersa® berberine Compared to standard berberine extracts, Rebersa® has several advantages: 1. Better for your stomach Do you have a sensitive stomach? Then you know that some supplements can really irritate it. Rebersa® Berberine is different: With its intelligent LongLifeLipoTech™ formula, berberine is released gradually into your body. Research shows that this technology can help reduce the direct contact of berberine with your stomach . (1) (2) 2. Better absorption in the body Regular berberine supplements are often not optimally absorbed by the body. Rebersa® Berberine uses LongLifeLipoTech™, a technology that encapsulates berberine in small fat particles called liposomes. Research suggests that this liposomal packaging may support berberine absorption in the body. (3) 3. Safe and clean Berberine is safe to use within the recommended dosage of up to 1500 mg per day , with few reported side effects such as mild stomach upset. This is evident from an analysis of 52 studies with over 4600 participants (4). Additionally, the patented Rebersa® extract has a purity of over 97%, making it free from unnecessary fillers and contaminants. And thanks to this high purity, Rebersa® prevents you from ingesting unwanted or harmful substances that are sometimes present in cheaper berberine extracts (5)(6). 4. High purity and consistent quality Sabinsa, the producer of Rebersa® Berberine, conducts rigorous testing to ensure the purity and consistent quality of the extract. The purity of this extract is over 97%, meaning each dose contains a consistent amount of berberine, ensuring reliable efficacy. (6) How does Rebersa® berberine work? Rebersa® Berberine is often used in supplements aimed at supporting healthy metabolism, such as maintaining normal blood sugar and cholesterol levels.* It works by influencing certain processes in your body, such as how cells use energy and how fats and sugars are processed. The science surrounding berberine is still developing. The available results are promising, but researchers continue to study its effects. (4) Good to know : Claims marked with (*) are pending European approval. Buy Rebersa® berberine: Discover Berberine Premium Curious about what berberine can do for your health? Then it's wise to choose a supplement that uses the patented Rebersa® extract . As you now know, this extract guarantees high purity and consistent quality, which is important for a reliable effect. Also, pay close attention to the dosage. Many supplements contain 500 mg of berberine per capsule , and for good reason. Scientific research shows that a daily intake of between 500 and 1500 mg of berberine can be effective, with little chance of side effects. (4) Tip : Start with the lowest dose (500 mg) and gradually increase to 1000 or a maximum of 1500 mg per day if necessary. This way you can get a good feel for how your body reacts. Our Berberine Premium contains the high-quality Rebersa® extract in this ideal dosage, thus offering you a good and reliable choice for using this natural substance daily. This way you can be sure that you receive an effective dose every day, with the quality you deserve. Ebrina van der Bijl Ebrina is a nutritionist with a deep commitment to healthy eating and a sustainable lifestyle, based in beautiful Portugal. Her passion for natural and organic products is at the heart of her work. With a background in Nutrition & Dietetics and experience in product development and writing, she translates complex scientific information into practical advice for a balanced lifestyle. Read more Sources used Sharma, V. M., Valsaraj, T. V., Sudeep, H. V., Raj, A., Kodimule, S., & Jacob, J. (2024). Preparation, characterization, in vitro and in vivo studies of liposomal berberine using novel natural fiber Interlaced liposomal technology. European Journal Of Pharmaceutics And Biopharmaceutics, 203, 114431. https://doi.org/10.1016/j.ejpb.2024.114431 Duong, T. T., Yen, T. T. H., Nguyen, L. T., Nguyen, T., Nguyen, T., Nghiem, T., Pham, H. T., Raal, A., Heinämäki, J., & Pham, T. (2022). Berberine-loaded liposomes for oral delivery: Preparation, physicochemical characterization and in-vivo evaluation in an endogenous hyperlipidemic animal model. International Journal Of Pharmaceutics, 616, 121525. https://doi.org/10.1016/j.ijpharm.2022.121525 Solnier, J., Zhang, Y., Kuo, Y., Du, M., Roh, K., Gahler, R., Wood, S., & Chang, C. (2023). Characterization and Pharmacokinetic Assessment of a New Berberine Formulation with Enhanced Absorption In Vitro and in Human Volunteers. Pharmaceutics, 15(11), 2567. https://doi.org/10.3390/pharmaceutics15112567 Zamani, M., Zarei, M., Nikbaf-Shandiz, M., Hosseini, S., Shiraseb, F., & Asbaghi, O. (2022). The effects of berberine supplementation on cardiovascular risk factors in adults: A systematic review and dose-response meta-analysis. Frontiers in Nutrition, 9. https://doi.org/10.3389/fnut.2022.1013055 Salem, MA, De Souza, LP, Serag, A., Fernie, AR, Farag, MA, Ezzat, SM, & Alseekh, S. (2020). Metabolomics in the Context of Plant Natural Products Research: From Sample Preparation to Metabolite Analysis. Metabolites, 10(1), 37. https://doi.org/10.3390/metabo10010037 Funk, RS, Singh, RK, Winefield, RD, Kandel, SE, Ruisinger, JF, Moriarty, PM, & Backes, JM (2017). Variability in Potency Among Commercial Preparations of Berberine. Journal Of Dietary Supplements, 15(3), 343–351. https://doi.org/10.1080/19390211.2017.1347227
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