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Basic Health Package

What is lutein?

Lutein is an important antioxidant found mainly in plants, vegetables and fruits.

This substance belongs to the carotenoid group (a group of natural pigments) and occurs naturally in fruits and vegetables (such as broccoli, bell peppers, kiwi, and grapes). Egg yolks are also a source of lutein.

Lutein supplements

For supplements, lutein is mainly extracted from marigold (Calendula officinalis).

This plant is mainly known as a raw material for calendula ointment, but it also contains a wealth of other valuable substances:

  • Marigold extract consists of approximately 20% lutein and also contains a small amount of zeaxanthin (approximately 1%), two substances that are very similar.
  • In addition to lutein and zeaxanthin, marigold extract also contains other substances, such as saponins, flavonoids and triterpenes.

These substances together enhance the effect of the marigold extract and make it widely applicable in health supplements.

Zeaxanthin and lutein

Both substances look very similar, but their atoms are arranged slightly differently.

You will often find lutein and zeaxanthin together in supplements. This is because they  reinforce each other in their work.

1. Yellow pigment, green vegetables

They also often occur together in nature. In many vegetables, fruits, and flowers, they are responsible for the yellow, orange, and red colors.

Are you also immediately thinking of carrots and yellow bell peppers? It's a bit different.

Lutein and zeaxanthin are mainly found in green leafy vegetables, such as spinach and kale. This is because these substances combine well with chlorophyll, the green pigment in plants.

So even though lutein and zeaxanthin are yellow pigments, they are actually found in vegetables that are green in color, rather than the yellow or orange vegetables you might expect.

2. Antioxidants

Lutein and zeaxanthin act as  Antioxidants. They help protect the body against free radicals, unstable molecules that can damage cells, proteins, fats, and DNA.

Because lutein and zeaxanthin complement each other, they enhance each other's effects and together they can help combat free radicals even more effectively.

They also contribute to the restoration of glutathione. Glutathione is another powerful antioxidant in your body that is important for protecting cells from damage.

3. Eye health

Lutein and zeaxanthin are also found in your eyes. They are the main carotenoids in the human lens. They help protect your eyes from light damage, especially in the macula, the central part of your retina.

Research has shown that taking 20 mg of lutein daily for at least 6 months can help support eye health, especially in people with age-related macular degeneration (AMD), an eye disease that often occurs later in life. (1) (2)

Multivitamin with lutein and zeaxanthin

Multi Premium is a high-quality multivitamin that contains the most absorbable forms of important vitamins and minerals.

Combined with antioxidants from Tagetes Erecta extract, Multi Premium provides a plant-based source of lutein and zeaxanthin, which help protect your eyes and brain.*

Sources used

  1. Liu, Y., Ni, M., Wu, R., Yang, Z., Zhu, X., & Chen, J. (2022). The level and efficacy of lutein in patients with age-related macular degeneration: a comprehensive systematic review and meta-analysis. Annals Of Translational Medicine , 10 (6), 299. https://doi.org/10.21037/atm-22-173
  2. Wilson, L.M., Tharmarajah, S., Jia, Y., Semba, R.D., Schaumberg, D.A., & Robinson, K.A. (2021). The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Advances in Nutrition , 12 (6), 2244–2254. https://doi.org/10.1093/advances/nmab071

 

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Association of vitamin C with the risk of age-related cataract: a meta-analysis. Acta Ophthalmologica, 94(3).  https://doi.org/10.1111/aos.12688 Zhang, Y., Jiang, W., Xie, Z., Wu, W., & Zhang, D. (2015). Vitamin E and risk of age-related cataract: a meta-analysis. Public Health Nutrition, 18(15), 2804–2814.  https://doi.org/10.1017/s1368980014003115 Wilson, L.M., Tharmarajah, S., Jia, Y., Semba, R.D., Schaumberg, D.A., & Robinson, K.A. (2021). The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis. Advances in Nutrition, 12(6), 2244–2254.  https://doi.org/10.1093/advances/nmab071 Lopresti, A. L., & Smith, S. J. (2025). The effects of lutein/zeaxanthin (Lute-gen®) on eye health, eye strain, sleep quality, and attention in high electronic screen users: a randomized, double-blind, placebo-controlled study. Frontiers in Nutrition, 12.  https://doi.org/10.3389/fnut.2025.1522302 Wang, W., & Ko, M. (2023). Efficacy of Omega-3 Intake in Managing Dry Eye Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal Of Clinical Medicine, 12(22), 7026.  https://doi.org/10.3390/jcm12227026 Lawrenson, J. G., & Downie, L. E. (2019). Nutrition and Eye Health. Nutrients, 11(9), 2123.  https://doi.org/10.3390/nu11092123 Khoo, H. E., Ng, H. S., Yap, W., Goh, H. J. H., & Yim, H. S. (2019). Nutrients for Prevention of Macular Degeneration and Eye-Related Diseases. Antioxidants, 8(4), 85.  https://doi.org/10.3390/antiox8040085 Pereira, A., Adekunle, R.D., Zaman, M., & Wan, M.J. (2023). Association Between Vitamin Deficiencies and Ophthalmological Conditions. Clinical Ophthalmology, Volume 17, 2045–2062.  https://doi.org/10.2147/opth.s401262

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A glass of orange juice with a meal does more than you think. 2. Copper Copper helps the normal functioning of the immune system. It's a trace element that helps form enzymes that protect your cells from damage. It also supports the activity of white blood cells . You will find a lot of copper in: Nuts and seeds (especially cashews and sunflower seeds) Whole grain products Crustaceans Liver Dark chocolate Did you know that you only need a small amount of copper? The reference intake for adults is around 0.9–1.0 milligrams of copper per day. Too much zinc or iron can actually hinder its absorption, so varying your diet is the best way to maintain that balance. 3. Selenium Selenium contributes to the normal functioning of the immune system. This mineral helps protect your cells from oxidative stress and is involved in the production of proteins used by your immune system. Selenium contributes to healthy cooperation between your immune cells. Recommended amount: Approximately 70 micrograms per day for men and 60 micrograms for women, according to the Nutrition Center. These foods are rich in selenium: Brazil nuts Meat and fish Eggs Whole grains Did you know that the amount of selenium you consume depends on where your food comes from? In the Netherlands, the soil naturally contains little selenium, meaning grains and vegetables provide less of this mineral. 4. Zinc Zinc supports your immune system in several ways. It helps in the production and renewal of immune cells and protects cells against oxidative stress released during immune responses. Your body can't store zinc, so it's important to get some every day. The recommended amount for men is 9 milligrams per day and for women 7 milligrams . You will mainly find zinc in these foods: Meat and poultry Whole grain products Nuts and seeds Legumes Dairy Did you know that pumpkin seeds are among the best plant sources of zinc? This is helpful if you eat less meat. Nutrition and lifestyle: The basis for your immune system Your immune system works best when your body gets everything it needs: Enough vitamins, minerals, sleep, exercise and rest. A healthy diet forms the foundation. It provides the building blocks your immune system needs to function normally. Exercise, sleep and relaxation then help to keep that system in balance, so that it does not react too strongly or too slowly. If you eat a varied diet, with plenty of vegetables, fruit, whole grains, legumes, nuts, fish and occasionally some meat or eggs, your body usually gets enough nutrients to keep your immune system functioning normally. A supplement to complement your diet Supplements can be a practical addition to a healthy lifestyle, especially at times when your body needs some extra support. Think of the winter months , when you get less sunlight , or periods of stress , fatigue or recovery , when your nutritional intake or absorption is temporarily less than optimal. 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Her passion for natural and organic products is at the heart of her work. With a background in Nutrition & Dietetics and experience in product development and writing, she translates complex scientific information into practical advice for a balanced lifestyle. Read more Sources used Mitra, S., Paul, S., Roy, S., Sutradhar, H., Emran, TB, Nainu, F., Khandaker, MU, Almalki, M., Wilairatana, P., & Mubarak, M. S. (2022). Exploring the Immune-Boosting Functions of Vitamins and Minerals as Nutritional Food Bioactive Compounds: A Comprehensive Review. Molecules, 27(2), 555.  https://doi.org/10.3390/molecules27020555 Paulsingh, C. N., Riaz, M. F., Garg, G., Umeano, L., Iftikhar, S., Alhaddad, S. F., & Hamid, P. (2024). Exploring the Impact of Personalized Nutritional Approaches on Metabolism and Immunity: A Systematic Review of Various Nutrients and Dietary Patterns. Cureus.  https://doi.org/10.7759/cureus.58553 Stefanache, A., Lungu, I., Butnariu, I., Calin, G., Gutu, C., Marcu, C., Grierosu, C., Goroftei, E.R.B., Duceac, L., Dabija, M.G., Popa, F., & Damir, D. (2023). Understanding How Minerals Contribute to Optimal Immune Function. Journal Of Immunology Research, 2023, 1–26.  https://doi.org/10.1155/2023/3355733 Stephen, A. I., & Avenell, A. (2006). A systematic review of multivitamin and multimineral supplementation for infection. Journal Of Human Nutrition And Dietetics, 19(3), 179–190.  https://doi.org/10.1111/j.1365-277x.2006.00694.x Fantacone, M. L., Lowry, M. B., Uesugi, S. L., Michels, A. J., Choi, J., Leonard, S. W., Gombart, S. K., Gombart, J. S., Bobe, G., & Gombart, A. F. (2020). The Effect of a Multivitamin and Mineral Supplement on Immune Function in Healthy Older Adults: A Double-Blind, Randomized, Controlled Trial. Nutrients, 12(8), 2447.  https://doi.org/10.3390/nu12082447

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In recent years, extensive research has been conducted into these benefits. Did you know? Brussels sprouts and red bell peppers contain more vitamin C than oranges. Scientifically proven benefits of vitamin C Below you will find 13 benefits of vitamin C, along with various scientific studies that support this: 1. Vitamin C protects against oxidative damage Vitamin C is primarily known as an antioxidant, meaning it helps combat free radicals in the body. These free radical compounds can cause damage when you have too much of them in your body. Your body uses antioxidants to keep these free radicals under control. Vitamin C contributes to protection against free radicals and external influences. This is good for maintaining healthy cells and tissues. (1) 2. Vitamin C is good for your blood vessels Healthy cardiovascular systems are important for everyone. All your organs depend on the blood supply. Unhealthy blood vessels can prevent various vital organs from receiving enough blood. Vitamin C contributes to the production of collagen in your body. Collagen is important for maintaining supple veins and strong blood vessel walls, among other things. A collagen deficiency is detrimental to your blood vessels. In fact, vitamin C is important for the health of your blood vessels, because collagen formation is essential for the proper functioning of the blood vessels. This has been shown in a study of obese children. (2) 3. Vitamin C is good for your bones Vitamin C is not only important for your blood vessels but also for normal bone function. For example, vitamin C contributes to the maintenance of strong bones and plays a role in bone formation. A study has shown that vitamin C is good for maintaining strong bones. No adverse effects have been reported, which suggests that vitamin C is safe to use. (3) A vitamin C deficiency affects collagen production. And collagen contributes to the maintenance of strong bones. Taking a vitamin C supplement is therefore good for your bones. This is measured based on bone mineral density. (4) 4. Vitamin C is good for your cartilage Healthy bones and healthy cartilage. Who wouldn't want that? Because vitamin C contributes to collagen production in your body, it's good for the production of cartilage in joints. Vitamin C is also good for maintaining healthy cartilage. Its antioxidant properties offer protection against inflammation in your joints. This has been shown in a study of the effect of vitamin C on cartilage health. (5) This is because the vitamin is water soluble and can therefore react with various aqueous free radicals and reactive forms of oxygen. A vitamin C deficiency can therefore lead to reduced collagen production. Joints contain a lot of collagen-rich connective tissue, which means a collagen deficiency could cause problems. Many studies have been done on the cause of joint problems related to collagen deficiency. (6) 5. Vitamin C is good for the iron levels in your blood Iron is an important mineral that plays a variety of roles in your body. For example, iron is essential for the production of red blood cells and the transport of oxygen. Vitamin C increases the absorption of iron from food by your body. In fact, 100mg of vitamin C has been shown to increase iron absorption by 67%. (7) Essentially, the vitamin provides your body with extra iron. This is very beneficial for people prone to iron deficiency, as it can help reduce the risk of anemia. An iron deficiency can lead to reduced red blood cell production, which causes anemia. Do you have low iron levels in your blood? Then vitamin C can help improve your iron absorption. (8) 6. Vitamin C is good for your immune system A strong immune system is important for staying healthy. This is also why most people take a vitamin C supplement. Vitamin C supports your immune system. Your immune system works with white blood cells, also called lymphocytes and phagocytes. They help protect your body and ensure the normal functioning of your immune system. (9) Because vitamin C is an antioxidant, it helps your white blood cells function better by protecting them from free radical damage. (10) Finally, vitamin C helps protect your body after strenuous physical exertion. Your immune system is weakened because your body is busy recovering. The protective effect of vitamin C provides support in this process. A vitamin C deficiency has been linked to poorer resistance, which helps protect your body. (11) Curious about ways to boost your immune system? Then be sure to read our article on natural ways to strengthen your immune system . This article contains 6 helpful methods for a stronger immune system. 7. Vitamin C is good for your skin Healthy skin gives you a well-groomed appearance. For this, it's important that you produce enough collagen. Vitamin C contributes to collagen production and thus to maintaining healthy skin. Vitamin C is a very important part of your skin's immune system. It's transported to your skin, where it can act as an antioxidant. This helps strengthen your skin from within. (12) Healthy skin contains a lot of vitamin C, especially in the outer layer of the skin. Vitamin C keeps your skin healthy by protecting it from oxidative damage caused by UV radiation and exposure to pollutants like cigarette smoke or ozone. (13) 8. Vitamin C is good for your psychological function Vitamin C is a powerful antioxidant that promotes mental resilience and a clear mind. It even has several benefits for your psychological function, such as improving your mood, learning performance, concentration, and memory. Vitamin C deficiency is involved in your memory and thinking ability. In addition, a high vitamin C intake has been shown to have a protective effect on your thinking and memory as you age. (14) It has also been shown that people with good mental balance and normal concentration have higher concentrations of vitamin C in their bodies compared to other people. (15) 9. Vitamin C is good for your mouth and teeth Beautiful, healthy teeth: that's something everyone wants. And vitamin C can definitely help! It contributes to collagen formation, which is good for maintaining strong teeth. Collagen can help heal wounds in your mouth. In addition, too little collagen has been linked to tooth loss. This is because collagen is made up of fibers found in the tissues that make up teeth and bones. (16) A collagen deficiency can cause weakened gums, which can lead to bleeding. A vitamin C supplement can help stimulate collagen production. (17) 10. Vitamin C is good for the regeneration of vitamin E Vitamin E is a fat-soluble vitamin that also functions as an antioxidant. This vitamin doesn't dissolve in water, unlike vitamin C. Vitamin E plays a role in regulating cellular metabolism, among other things. Vitamin C can help maintain the activity of vitamin E by returning vitamin E to its active form. (18) I'll try to explain it simply for you... Vitamin C and vitamin E are both antioxidants, meaning they protect your body from free radical damage. Vitamin C scavenges water-soluble free radicals (outside your cells), while vitamin E scavenges free radicals within your membranes (inside your cells). When vitamin E attacks free radicals within your membranes, the vitamin binds to them. Vitamin C regenerates vitamin E by essentially taking over these free radicals from vitamin E, so they have a place to fight new free radicals in your cells. This even happens through your membranes, so vitamin C doesn't have to enter your cells for this. (19) 11. Vitamin C is good for your nervous system Your nervous system is essentially a network of nerves that receive information from your senses and transmit it to your brain. Your brain also sends signals to the rest of your body via your nervous system. In fact, your nervous system ensures that your entire body is connected. Your brain and spinal cord form the central part of your nervous system. The connections from there to your muscles and organs form the peripheral part of your nervous system. These two parts work together to keep your body functioning optimally. Vitamin C contributes to the normal functioning of your nervous system. This means it plays an important role in the functioning of your nerves. This is because it is an important antioxidant and therefore participates in many different cellular functions. (20) 12. Vitamin C supports your energy levels Your body produces energy in the form of ATP. This molecule is comparable to gasoline, which powers your car. ATP is produced in your mitochondria. This is one of the organelles in your body's cells, just as the engine is a component of your car. Mitochondria produce energy. Some cells that use a lot of energy (like muscles) have thousands of mitochondria, while other cells have only a few hundred. In your mitochondria, proteins, fats, and carbohydrates are converted into energy in the form of ATP. (21) Energy production in your mitochondria is vital to life and plays a role in many bodily processes, such as your physical strength and endurance. Mitochondria can be damaged and even die when exposed to free radicals. Vitamin C contributes to normal energy-yielding metabolism because it helps protect your body against these free radicals and promotes your energy metabolism. (22) 13. Vitamin C helps with fatigue Fatigue can have many different causes. It's not always immediately clear why you're so tired all the time. However, vitamin C has been proven to help reduce fatigue. As previously discussed, vitamin C is good for your blood iron levels. This iron level is responsible for healthy oxygen transport in your blood. Too little oxygen to your body's cells can, in turn, lead to fatigue. (23) One of the first signs of a vitamin C deficiency is fatigue. Fatigue can even occur before a complete deficiency develops. A vitamin C supplement can help counteract these symptoms after just a few days of moderate intake or within 24 hours of a high dose of vitamin C. (24) Vitamin C is a versatile supplement In this article, we've outlined 13 scientifically proven benefits of vitamin C. If you're considering taking a vitamin C supplement to supplement your diet, there are several important things to know. The general maintenance dose of vitamin C for adults is 1-2 grams per day. It's best to use vitamin C in combination with other antioxidants. This creates a strong interaction because they essentially "recycle" each other. Also, always make sure you use a high-quality vitamin C supplement! Lars Keijzers Lars is a biobased chemist with an insatiable interest in nutrition and science. He also enjoys exploring personal development and can be found regularly at the local gym. Read more

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